BDBM50093351 CHEMBL3585362

SMILES COc1cc(cnc1Cl)N1CCc2nc(NC(=O)NCCc3cn(CC(F)F)cn3)sc2C1

InChI Key InChIKey=MFASFQBUVZVOCJ-UHFFFAOYSA-N

Data  9 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093351   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093351(CHEMBL3585362)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of PI3Kbeta in human THP1 cells assessed as inhibition of CSF1-stimulated chemotaxis pre-incubated for 1 hr before MCP1 stimulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed